The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7, 12-dimethylbenz[a]anthracene

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The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression.

Biochanin A is an isoflavone isolated from red clover (Trifolium pratense), and is a commercially available nutraceutical for women suffering from postmenopausal symptoms. Isoflavones resemble the structure of oestrogen, and display agonistic and antagonistic interactions with the oestrogen receptor. Overexposure of oestrogen is a major contributing factor in the development of breast cancer, a...

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Red Clover (Trifolium pratense)

Brief Background: Red clover is a legume, which like soy contains "phytoestrogens" (plant-based compounds structurally similar to estradiol, capable of binding to estrogen receptors as an agonist or antagonist). Red clover was traditionally used to treat asthma, pertussis, cancer, and gout. In modern times, isoflavone extracts of red clover are most often used to treat menopausal symptoms, as a...

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Red clover (Trifolium pratense).

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Isoflavone content in red clover (Trifolium pratense L.) as related to nitrogen and phosphorus application rate

Red clover (Trifolium pratense L.) as a dietary supplement is currently used to treat menopausal symptoms because of its high concentrations of mildly estrogenic isoflavone. The application rate of N and P fertilizer has a huge influence on the isoflavone content (IC) in red clover. Trifolium pratense ‘Minshan’ is a unique plant resource in the alpine pasture region of northwest China. It plays...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 2003

ISSN: 0007-1145,1475-2662

DOI: 10.1079/bjn2003868